Archive for September, 2010

The Link Between Esophageal Spasms And Acid Reflux

September 27th, 2010
Kathryn Whittaker asked:




Those who suffer from acid reflux and are looking for some acid reflux relief may experience more than complications other than bile reflux. Some acid reflux sufferers experience spasms in their esophagus. Your esophagus connects your throat to your stomach and is structured like a long tube. A healthy esophagus moves food to the stomach through a series of synchronized muscle contractions. Esophageal spasms upset this natural process creating many unpleasant symptoms.

What is an esophageal spasm?

Esophageal spasms occur when the muscle contractions within the esophagus lack coordination and prevent food from properly moving through your esophagus to the stomach. Esophageal spasms affect the muscles that are situated within the walls of the lower esophagus. They can occur in the following two ways:

1. Diffuse spasms – This is when food traveling to the stomach is slowed due to irregular or simultaneous contraction of the esophageal muscles.

2. Nutcracker esophagus – This is when food progresses normally to the stomach, but the muscle contractions are abnormally strong and painful.

Researchers are not exactly sure what causes esophageal spasms, but one theory is that extremely cold, hot or spicy food can trigger a spasm. Another theory is that GERD or heartburn, which causes irritation and inflammation in the esophagus, can trigger a spasm. Whatever the real reason, one fact remains – People who are prone to acid reflux and have GERD are more prone to esophageal spasms, and the chances of developing this condition increases as they age.

The following are some symptoms of this condition that you should be aware of:

- Chest pain that is usually intense and is often mistaken for heart pain. This is the most common symptom.

- Pain when swallowing

- Trouble swallowing

- Feeling something is stuck in the throat

- Regurgitating food

- Heartburn

How are esophageal spasms diagnosed?

This condition can be hard to diagnose due to the fact that its symptoms closely resemble other disorders such as GERD. Nevertheless, should your doctor expect that you suffer from esophageal spasms; the condition may be diagnosed through -

- Barium esophagram – This is the most common test for people who suffer from trouble swallowing. The Barium esophagram utilizes X-rays to examine the esophagus and is the best test for detecting esophageal spasms.

- Esophageal CT scan – This is a test that uses computerized tomography (CT) scans to create and capture cross-sectional sliced images of the inside of the body. The test may reveal that the esophageal muscles have abnormal thickness which could mean esophageal spasms.

- Esophageal manometry test – This test involves the insertion of a thin tube into the esophagus via the mouth or nose. The purpose is to measure how effective the esophageal muscles are during the swallowing process.

Is there treatment for esophageal spasms?

Yes. The following are some suggested treatments:

- Manage underlying conditions – If you are prone to heartburn or suffer from GERD, manage these conditions to reduce your chance of spasms.

- Lifestyle changes – Change your eating habits such as avoid eating certain foods including those that are spicy or acidic, and avoid lying down directly after eating meals. Lifestyle change is also the best way to prevent esophageal spasms from occurring.

- Biofeedback – This is an alternative therapy that teaches you to use your mind to control your body. Electrical sensors help you recognize the way your body responds to psychological stress so you can control it.

- Medication – Muscle relaxants including nitrates or calcium channel blockers are often prescribed to reduce the severity of muscle contractions. Tricyclic antidepressants may also be recommended to help relieve pain.

- Surgery – This treatment is extremely rare but sometimes is the only option in serious cases. Myotmy may be performed to help weaken muscle contractions, or an esophagectomy (the removal of the esophagus) may be needed.



Butalbital APAP caffeine

Sleep Apnea Causes High Blood Pressure

September 27th, 2010
Judith Airey asked:




Sleep apnea is the repeated pausing of breathing while sleeping, so that one or more breaths are missed. A person can have many occurrences a night and in some people, episodes may last for up to minute. At each incident the brain awakens the person for a moment, to make them inhale air again. This cycle of brief awakenings results in disturbed and poor quality rest. Sleep apnea is not the same as snoring, though most people with this condition do snore.

Blood pressure normally falls during sleep. There is a substantial amount of evidence that if there is no fall at night, there is an increased risk of cardiovascular disease, including stroke and heart failure.

One of the side effects of sleep apnea is that blood pressure usually does not fall at night. This means that there is an increased risk of cardiovascular disease. Additionally if left untreated, there is an increased likelihood of having daytime (resting) high blood pressure too.

Some estimates are that 50% of long-term sufferers have high blood pressure. It is not clear whether the cause is the repeated shortage of oxygen, caused by missing breaths, or the interrupted and poor quality of sleep. It is probably a combination of both. Studies have shown that continually not getting enough sleep increases the risk of elevated blood pressure. The lack of continual deep sleep due to sleep apnea may have a similar effect.

Those with sleep apnea usually cannot tell that they have this condition, since they are not aware of stopping breathing and the brief awakenings. Consequently, many sufferers do not believe that they have this problem. when others tell them.

The National Heart, Lung and Blood Institute estimates that 18 million people have sleep apnea. This is a large number of people who are at greater risk of increased blood pressure.

There are a number of treatment options for sleep apnea depending on the cause. Sometimes lifestyle changes are sufficient, and can include, not lying on the back, sleeping with head and upper body elevated (such as in a recliner) a reduction in alcohol consumption, reduction in the use of muscle relaxants, quitting smoking and weight loss. There are a number of devices that fit in the mouth that are worn at night. Positive airway pressure devices are available also. A good place to start for more information about the causes and treatment is the American Sleep Apnea Association.

Treatment will decrease the risk of getting high blood pressure. For those who already have high blood pressure, treatment will help stop further increases, and reduce the risk of the consequences such as stroke and heart failure.

Butalbital APAP Caffeine, Fioricet, Tramadol

Amoxicillin Side Effects

September 27th, 2010
Amoxicillin asked:


As with other penicillins, in May it is expected that the side effects are mainly limited to sensitivity phenomena. They are more likely to occur in people who have shown hypersensitivity to penicillin and people with a history of allergy, asthma, hay fever or hives. The following adverse reactions have been reported as being associated with the use of penicillins:



Infections and Infestations: Mucocutaneous candidiasis.

Gastro-intestinal: nausea, vomiting, diarrhea, tongue and hair black hemorrhagic / pseudomembranous colitis.

The symptoms of pseudomembranous colitis in May occur during or after antibiotic treatment.

Hypersensitivity reactions: anaphylaxis

Serum sickness reactions, erythematous maculopapular rash, erythema multiforme, Stevens-Johnson syndrome, exfoliative dermatitis, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, hypersensitivity vasculitis and urticaria have been reported.

NOTE: These hypersensitivity reactions May be controlled with antihistamines and, if necessary, systemic corticosteroids. Whenever such reactions occur, amoxicillin should be discontinued unless, in the opinion of the physician, the condition being treated is life-threatening and supportive only to amoxicillin therapy.

Liver: A moderate rise in AST (SGOT) and / or ALT (SGPT) have been reported, but the importance of this observation is unknown. Hepatic dysfunction, including cholestatic jaundice, hepatic cholestasis and acute cytolytic hepatitis have been reported.

Renal impairment: The crystalluria has also been reported.

Hemic and lymphatic system: anemia, including hemolytic anemia, thrombocytopenia, thrombocytopenic purpura, eosinophilia, leukopenia and agranulocytosis have been reported during treatment with penicillin. These reactions are usually reversible after discontinuation of therapy and are believed to be hypersensitivity phenomena.

Central Nervous System: Reversible hyperactivity, agitation, anxiety, insomnia, confusion, convulsions, behavioral changes, and / or dizziness have been reported rarely.

Miscellaneous: Tooth discoloration (brown, yellow, or gray staining) has been rarely reported. Most reports occurred in pediatric patients. Discoloration was reduced or eliminated by brushing or dental cleaning in most cases.

Association with Clarithromycin and Lansoprazole: In clinical trials using combination therapy with amoxicillin and clarithromycin and lansoprazole, and amoxicillin plus lansoprazole, no adverse reactions peculiar to these drug combinations were observed. Adverse reactions that occurred were limited to those already reported with amoxicillin, clarithromycin, or lansoprazole.

Triple therapy: Amoxicillin / Clarithromycin / Lansoprazole The most frequently reported adverse reactions in patients who received triple therapy were diarrhea (7%), headache (6%) and taste perversion (5%). No treatment side effects were observed at significantly higher rates with triple therapy than dual therapy regime.

Dual Therapy: Amoxicillin / Lansoprazole The most frequently reported adverse reactions in patients who received amoxicillin three times a day, three times a day, lansoprazole dual therapy were diarrhea (8%) and headache (7%). No treatment side effects were observed at significantly higher rates with amoxicillin three times a day, three times daily dual therapy of lansoprazole lansoprazole alone.

For more information on adverse reactions with clarithromycin or lansoprazole, refer to their package inserts, adverse reactions.

carisoprodol