Archive for November, 2010

Mechanism of Action and Increased Fluoxetine Dosage

November 30th, 2010
cecilia asked:




As a selective serotonin re-uptake inhibitor or SSRI drug, the mechanism of action of fluoxetine is by increasing the level of serotonin in the brain. It has been suggested that patients with depression have lower levels of serotonin in their brain. Fluoxetine eases the symptoms of depression by treating this serotonin imbalance in the brain.

 

Serotonin is one of the neurotransmitters present in the brain which is easily reabsorbed once it is released. The mechanism of action of fluoxetine is to inhibit or slow down the metabolism of this neurotransmitter in order for the brain to have higher levels of serotonin. Patients with increased levels of serotonin were found to usually recover from their symptoms.

 

SSRI drugs like fluoxetine have been found to also help in the growth of new neurons, commonly called nerve cells, in patients. Neurons are very essential in facilitating information in the brain. It has been suggested that growth of new neurons allows the brain to have more room for processing new thoughts, memory, emotions, and motivations. Fluoxetine and other serotonin inhibitors hastens the growth of new nerve cells in the part of the brain responsible for improving the moods of the patients.

 

Since it often takes a longer time to treat the symptoms of depression, increasing fluoxetine doses is usually done. Doctors usually start a patient’s medication on a lower dose before gradually increasing fluoxetine doses as the symptoms react on the drug. Improvement and prevention of a possible relapse of depression are the usual effects of increasing fluoxetine doses in patients.

 

Patients should not be alarmed that toxic effects from increasing fluoxetine levels may arise once their doctor suggests a higher dose. SSRI drugs are considered one of the safest antidepressant drugs that also cause the least number of side effects. Although SSRI drugs treat depression in the same manner, their side effects may vary in different patients. Possible side effects like nausea, diarrhea, headache, lack of sexual drive, drowsiness, and insomnia may be experienced but this depends in every patient. Some patients may have these side effects while others may not. These side effects can also diminish as the doctor adjusts the fluoxetine dose prescribed.

 

Increasing the level of fluoxetine dose to be taken is just normal in long-term medications and it doesn’t mean that doctors will always increase the patients’ dose. It is only done as the symptoms progress. This increases the patients chance of recovery and reduces the risk that the symptoms may come back once the medication is complete. Once the symptoms of depression diminish, doctors can start to decrease the fluoxetine dose to be taken. In this way, withdrawal symptoms from suddenly stopping the medication can be prevented. The dose may be decreased gradually every 2 weeks until the patient no longer has to take any dose.

 

Fluoxetine is one of the dependable drugs for the treatment of depression. It is important that patients understand that increasing fluoxetine doses is not intended to cause them any harm and that it is just a normal part of their treatment. It is one way of improving the drug’s efficacy in treating depression.



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Stress headache symptoms

November 30th, 2010
Stewart Goh asked:




Experiencing occasional headaches that are just too hard to handle? These headaches might be due to stress related reasons and are called stress headaches or tension headaches.

Stress headaches can be categorized into two; episodic basis and chronic basis where episodic basis refers to headaches that occur less than 15 days per month whereas chronic basis is when the headaches occur for more than 15 times per month or even daily. There are many stress headache symptoms to look out to as they may eventually cause adverse side effects.

Examples of symptoms that may occur due to this kind of headaches include pain that begins at the back of the head and also the upper neck which can be described as band-like tightness or even pressure.

Besides that, the pressure mounts at the head and the most severe pain can be felt at the eyebrows. The headaches are usually insignificant and not disabling but it affects both sides of the individuals head. Regardless of that, daily tasks can still be performed.

Stress headaches are mainly due to certain factors such as physical and emotional stress. Physical stress comprises of prolonged labor or poor working ergonomics meanwhile emotional stress relates mostly towards the individuals emotional state. Besides that abuse of substances such as cigarettes, alcohol and caffeine may also lead to headaches related to pressure and stress.

Stress headaches symptoms if discovered and treated at an early stage may reduce the risk of even serious health hazards. Prescriptions such as ibuprofen and aspirin are some of the example of medication available but the most effective method would be by attending stress management classes.



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Top Tips To Treat Neck Pain

November 29th, 2010
Raymond Geok Seng Lee asked:




The neck bones are a continuation of the spine. The top seven vertebrae are called cervical or neck vertebrae. The seventh one makes the prominent bump that you can feel where your back joins your neck. The upper-most vertebrae, the Atlas, holds up the skull. The second vertebrae, the Axis, has a vertical peg around which the head turns. The entire neck is more flexible than the back. It bears less weight but also is less well protected by thick muscles. The disc spaces in the neck can get narrow, bony spurs can form, and nerves can get caught and compressed, just as in the low back. Arthritis such as spondylitis or rheumatoid arthritis can affect the neck, and rheumatoid arthritis is particularly likely to affect the top two vertebrae, allowing the head to slip forward and backward.

Excess tension in the neck muscles can cause neck pain as well, and is probably the most common cause of neck pain. Here the pull on the ends of the ligaments causes pain in the back of the head where the neck attaches to the skull, and this pain can often shoot forward and be interpreted as a headache.

Usually, as in the low back, a neck problem is minor and will be self-limited; however, injuries do take some time to heal. Healing depends on natural healing processes. Excessive neck movement tends to slow the healing and has the possibility of causing re-injury.

Rest the neck and listen for what the pain message tells you not to do. You can fold a bath towel lengthwise so that it is a four-inch-wide strip, and wrap the neck with it, securing it comfortably with a safety pin or tape. Now you have a soft neck brace to wear at night, and this will clear up nearly half of all neck pain problems. If pain persists, use the soft collar during the day as well or buy a commercial soft collar to wear. You want some support from the collar, but more than that you want a little reminder not to turn your head too far or too fast.

Common sense says to watch out for things that aggravate the pain and to avoid them. Watching a tennis match is obviously not a good idea because of the repeated head turning required. You probably engage in other activities that require head turning and are just as damaging. For example, some people get help by wearing their glasses while reading because this enables them to be farther away from the book. Try to sit back farther from your work. Don’t reach or look over your head to get objects; use a stool.

Keep painkillers and muscle relaxants to a minimum or avoid them altogether. Aspirin, acetaminophen, or ibuprofen is all right but probably won’t make you feel better.

Sleep on a good firm mattress. Don’t sleep on your stomach, and if you sleep on your side, place a pillow so that your neck is in a neutral position, not propped up or hanging down. When sleeping on your back, use a small pillow, and place it beneath your neck as well as your head.

The time for exercise begins as the pain subsides, usually after five to seven days. Don’t rush. There are two types of exercises, stretching and strengthening, and you should do some of each. They are designed to help prevent recurrence. Start stretching exercises with gentle stretches and increase the stretches slowly, day by day. There are three maneuvers: chin toward chest, ear toward shoulder, and looking to the side. The last two should, of course, be done in each direction. Do them twice daily, each maneuver three times gently.

Strengthening exercises can begin at the same time and should start with three repetitions, twice daily. Slowly work up to ten repetitions. If you have been having recurrent neck problems, these exercises are a worth-while lifetime habit. Here are three:

1. (Shoulder shrug) Raise both shoulders towards ears, hold for two seconds, relax, repeat.

2. Take a deep, deep breath, hold for five seconds, release, repeat. The neck muscles are “accessory muscles of respiration” and breathing exercises involve the neck muscles.

3. While standing with both hands behind your back, grab one thumb with your other hand. Flex your head way back. Press down with your hands. Take a deep breath, relax, repeat. This exercise can be done lying on your stomach as well, after you get good at it standing up.

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