Archive for November, 2010

Delivering Opportunities in the Inhalable Drugs Market: Innovative formulations and devices -Aarkstore Enterprise

November 28th, 2010
Minal asked:




The delivery of drugs using inhaled formulations is currently heavily underexploited except for the treatment of respiratory diseases. However, the large surface area offered by the lungs offers the opportunity to achieve rapid absorption of drugs from suitable inhaled formulations. It represents an opportunity to provide an effective delivery route for therapeutics, such as proteins, that are suitable for oral administration. The delivery of insulin via inhalation has been suggested as a major commercial opportunity, However, commercial success necessitates identifying stable and effective formulations, combined with a suitable, convenient, device for delivering the inhaled formulation.

This report evaluates the current state of the inhaled market, examining the currently limited impact of inhaled formulations in non-respiratory segments and the dominance of the respiratory market, a major market segment, by inhaled formulations. It examines the formulations currently in development for both non-respiratory and respiratory indications as well as summarizing the inhaled formulations of new chemical entities being developed for the treatment of respiratory disease. The development of methods of delivering biological products by inhalation is highlighted as a major opportunity for growth. The value of formulation and inhaler developments is highlighted by case histories that show how they can play a key role in product lifecycle management, by building and sustaining blockbuster revenues; while not providing suitable inhalers can lead to high profile, and very costly, failure. The critical role of specialist companies in advancing technological developments with inhalers and inhaled formulations is highlighted, with the commercial opportunities that can be afforded by partnerships with such companies examined.

Key features of this report



•Analysis of inhaled drug market for both respiratory and non-respiratory indications.

•Detailed analysis of inhaled respiratory market, both by chemical entity/formulation and by inhaler device type.

•Discussion of inhaled formulations in development and assessment of opportunities offered, highlighting the current emphasis on developing new combination formulations and the challenges of developing inhaled protein formulations.

Scope of this report



Key Market Issues



•Inhaled therapeutics represent a significant segment of the pharmaceutical market, generating revenues of $26.3 billion in 2008, and accounted for 78% of the revenues in the respiratory market segment.

•Growth opportunities are provided by the development of inhaled formulations of new chemical entities, or by developing and establishing inhaled formulations of other classes of agent, especially protein therapeutics.

•The high value of the combination steroid long acting b2 agonist segment ($10 billion) provides considerable opportunities for third parties to develop competing formulations of generically available agents.

Key findings from this report



• Revenues from inhaled therapeutics for non-respiratory indications are modest.

• Inhaled therapeutics dominate the respiratory market segment.

• There is increasing emphasis on the use of, and developing new, dry powder inhalers.

• The use of nebulizers is confined to certain classes of drug and specific indications, in part due to their size and lack of portability.

• Pressurized metered dose inhalers remain a key delivery option for some classes of drug.

• Inhaled combination formulations represent substantially the most valuable class of inhaled therapeutics.

Key questions answered



• Where are the major opportunities in the inhaled therapeutic market?

• What strategies should be considered in developing inhaled products?

• Which companies have an expertise in developing proprietary inhaler devices?

• Which companies have expertise in developing inhaled formulations?

• Where are the commercially viable opportunities for developing inhaled formulations of systemically acting agents?



 

for more information,please visit:

http://www.aarkstore.com/reports/Delivering-Opportunities-in-the-Inhalable-Drugs-Market-Innovative-formulations-and-devices-44797.html



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Does a pain management doctor specialize in medication or what?

November 27th, 2010
Rhymenoserus asked:


I’m curious because I’m having back surgery next week and my primary has been prescribing my meds. We talked and he wants me to find a specialist for meds after surgery. Who can I go to, my surgeon is 4 hours away so he said find someone local is that pain management or is that something else.

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Stress Triggers Back Pain

November 27th, 2010
Pierre Gabriel Duncan asked:




Stress and other emotional factors are believed to play a major role in low back pain, particularly chronic low back pain. Many people unconsciously tighten their back muscles when they are under stress, studies revealed.

Low back pain is used to describe a range of symptoms. Depending on the cause, low back pain may be dull, burning, or sharp. It may be felt at a single point or over a broad area.

It can come on gradually or suddenly and may occur with muscle spasms or stiffness.

Back pain can either be acute or chronic. Acute lasts for less than three months and most people gain relief after about 4 to 6 weeks of home treatment.

Chronic on the other hand lasts longer than three months.

Experts said stress causes tense muscles which are tight and feel “hard” to the touch.

People who are stressed often have neck, shoulder, and low back pain. This may be caused by constant tension in the muscle because of stress. Stress also affects rheumatoid arthritis.

Easy remedies

For chronic back pains, simple home remedies will ease the pain. Applying ice for 5 to 15 minutes every two or three hours will do a lot of help. Taking a hot shower or using a heating pad or hot water bottle can do wonders for some.

Others opt the fast and easy relief from pain medicines like Tramadol. Taking Tramadol on a regular schedule usually works best instead of waiting until the pain is severe. A number of online pharmacies including drugstoretm.com. carry Tramadol.

For the first day or two, rest in a comfortable position. Try lying on your side with a pillow between your knees. Or lie on your back on the floor with a pillow under your knees.

Medical experts advise patients to get back to their normal activities as soon as possible. Movement helps your muscles stay strong. Staying in bed for more than 1 or 2 days, they said, can actually make the problem worse.

Walking is the simplest and perhaps the best exercise for the lower back.

However, if symptoms are severe or pain does not stop even after two weeks of self care, it is best to consult a doctor. Stronger pain medicines and physical therapy may be necessary.

Strive to make your lives stress-free as stress is one of the main causes of back pains.

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